Thinking About Concussion
2017-18 CUSP Distinguished Speaker Series
Tuesday, October 10, 2017
Traumatic brain injury (TBI) continues to be a major socio-economic problem with about two million head injuries in the US annually, the majority being mild in severity—what we call concussion. Recent studies from the laboratory suggest that concussion, the inability to think clearly, may be due, in part, to a disruption of dendritic organization and function resulting in the inability to make new memories. Working with tissue culture models of TBI, we have identified therapeutic interventions that rescue neuronal plasticity that underlies learning.
Barclay Morrison received his B.S. degree in biomedical engineering from the Johns Hopkins University, his M.S.E and Ph.D. degrees in bioengineering from the University of Pennsylvania, and continued his academic training as a post-doctoral fellow in the Clinical Neurosciences department at Southampton University, UK. He is currently Professor of Biomedical Engineering and Vice Dean of Undergraduate Programs in the Fu Foundation School of Engineering and Applied Science at Columbia University. His research focus is on the biomechanics of traumatic brain injury at the tissue level, as well as, the biochemical, genomic, and molecular pathways responsible for post-traumatic dysfunction. He applies a quantitative approach to understand the relationship between mechanical injury parameters and the living biological response of the injured tissue. He currently serves as the vice president for the International Research Council on the Biomechanics of Injury and is associate editor for the Journal of Biomechanical Engineering and the Journal of Neurotrauma.